In the period from March to June 2017, 3 new manuscripts and 1 thesis were published in the field of food allergy (co-)authored by the TNO Food Allergy team.
One paper described the current mechanistic understanding of sensitization induction to food proteins by applying the concept of adverse outcome pathway (AOP):
- Application of the adverse outcome pathway (AOP) concept to structure the available in vivo and in vitro mechanistic data for allergic sensitization to food proteins.
van Bilsen JHM, Sienkiewicz-Szłapka E, Lozano-Ojalvo D, Willemsen LEM, Antunes CM, Molina E, Smit JJ, Wróblewska B, Wichers HJ, Knol EF, Ladics GS, Pieters RHH, Denery-Papini S, Vissers YM, Bavaro SL, Larré C, Verhoeckx KCM, Roggen EL. Clin Transl Allergy. 2017 May 12;7:13. doi: 10.1186/s13601-017-0152-0. eCollection 2017. Review. PubMed PMID: 28507730; PubMed Central PMCID: PMC5429547
In a second paper the risk of an unexpected allergic reaction from residual peanut protein in highly refined vegetable oil for the peanut allergic population was assessed:
- Assessing food allergy risks from residual peanut protein in highly refined vegetable oil.
Blom WM, Kruizinga AG, Rubingh CM, Remington BC, Crevel RWR, Houben GF.Food Chem Toxicol. 2017 May 31;106(Pt A):306-313. https://authors.elsevier.com/a/1VFGi-NViv0ah
Finally, the impact of extensive heating of hen’s egg and cow’s milk on threshold dose distributions was studied:
- Minimal impact of extensive heating of hen’s egg and cow’s milk in a food matrix on threshold dose-distribution curves.
Remington BC, Westerhout J, Campbell DE, Turner PJ. Allergy. 2017 May 5. doi: 10.1111/all.13198. [Epub ahead of print] PMID: 28474471 [PubMed – as supplied by publisher]
A thesis by Henrike Broekman addressed the allergenic risks of proteins from mealworm and other insects as potentially novel food proteins:
- Allergenic risks of mealworm and other insects; An approach to assess the risks of new food proteins in allergic patients
Henrike Casparina Helena Petronella Hustinx-Broekman, University of Utrecht, ISBN 9789462956087
Several of the chapters contained in the Thesis also appeared as papers in peer reviewed literature.
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