Food-borne Factors in Allergic and Inflammatory Diseases

TNO in collaboration with University Medical Centre Utrecht performs research on food-borne factors in allergic and inflammatory diseases. Our interest in this program mainly concerns the identification of factors that, either or not in interaction with the gut microbiome, influence the inflammatory state of our body. We aim to elucidate how we can use diet as an intervention or to support interventions in immune health, to develop better diagnosis, patient stratification, and population and personalized management, therapy and prevention of inflammatory diseases.

We collect data from a wide variety of substances (up to 25.000!) in food through various databases. We link this data to food intake data from, for example, cohort studies, to map intake through food at substance level. We combine this with individual microbiome data and patient/health characteristics data to search for (complex combinations of) food-borne factors that influence the inflammatory state using machine learning approaches. You can find more information on our approach here.

We welcome industrial partners interested in studying food-borne factors in allergic and inflammatory diseases to identify nutritional targets for intervention or to support interventions in immune health. For more information, please contact: geert.houben@tno.nl